Kanunnik Donatianus Joannes Arents, 1690-1757.
نویسندگان
چکیده
منابع مشابه
Op-brhe150265 1757..1758
SSc is a heterogeneous autoimmune CTD characterized by widespread vasculopathy, formation of autoantibodies and varying degrees of skin and major organ fibrosis [1, 2]. The life-threatening nature of this disease is well depicted by a 5-year mortality of 30 50% in a subset of patients with dcSSc and internal organ involvement. Despite the substantial research over the past decade, the aetiology...
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The early visual system is endowed with adaptive mechanisms that rapidly adjust gain and integration time based on the local luminance (mean intensity) and contrast (standard deviation of intensity relative to the mean). Here we show that these mechanisms are matched to the statistics of the environment. First, we measured the joint distribution of luminance and contrast in patches selected fro...
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Variability in drugpharmacokinetics is amajor factor in defining drug efficacy and side effects. There remains an urgent need, particularly with the growing use of polypharmacy, to obtain more informative experimental data predicting clinical outcomes. Major species differences in multiplicity, substrate specificity, and regulation of enzymes from the cytochrome P450–dependent mono-oxygenase sy...
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Omeprazole (OME), a proton pump inhibitor used to treat gastritis, is also an aryl hydrocarbon receptor (AhR) activator. OME activates AhR in human hepatocytes and hepatoma cells, but not in mice in vivo or in vitro. We recently discovered that this species-specific difference results from a difference in a few amino acids in the ligand-binding domain of AhR. However, OME activates both mouse a...
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Background: Uncertainty exists regarding the effects of iron supplementation on neurodevelopmental outcomes in the absence of anemia. Objective: Our objective was to evaluate the effects of iron supplementation in nonanemic pregnant women and in nonanemic healthy children aged ,3 y on the mental performance and psychomotor development of children. Design: In this systematic review, MEDLINE, EMB...
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ژورنال
عنوان ژورنال: Handelingen van het Genootschap voor Geschiedenis
سال: 1982
ISSN: 0770-0822
DOI: 10.21825/hvgg.v119i1-2.4458